Characteristics of an adenosine A1 binding site in human placental membranes
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چکیده
منابع مشابه
Characteristics of an adenosine A1 binding site in human placental membranes.
Binding sites were solubilized from human placental membrane using 1.5% sodium cholate and were assayed using polyethylene glycol precipitation. These soluble binding sites had properties of an adenosine A1 binding site. 2-[3H]Chloroadenosine and N-[3H]-ethylcarboxamidoadenosine (NECA) binding were time dependent and reversible. Scatchard plots indicate two classes of binding sites with Kd valu...
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Human A1 adenosine receptor gene expression is controlled by two independent promoters. The upstream promoter, promoter A, is subject to tissue specific regulation because not all cells express the mRNA associated with this promoter. One potential regulatory sequence located downstream of the TATA box is an AGG element appearing in a tandem repeat. In a previous study, transient transfection as...
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ژورنال
عنوان ژورنال: Archives of Biochemistry and Biophysics
سال: 1989
ISSN: 0003-9861
DOI: 10.1016/0003-9861(89)90579-1